The Science: Research published in the Journal of Dermatological Science reveals that collagen production decreases by approximately 1% per year starting in our 20s [1]. By age 80, overall collagen levels drop by up to 75%. This decline occurs because the TGF-β/Smad pathway—a critical regulator of collagen production in fibroblasts—becomes less active with age [2]. Additionally, enzymes that break down collagen (matrix metalloproteinases) increase, creating a double impact of reduced production and accelerated breakdown.

What This Means For You: The carefully selected ingredients in Skin Glow work directly on these pathways, helping to both stimulate collagen production and inhibit excessive breakdown. This dual-action approach addresses the root causes of skin aging rather than just treating surface symptoms, helping to maintain skin firmness and elasticity even as natural collagen production declines.

The Science: Research published in the Journal of Investigative Dermatology demonstrates that low-grade chronic inflammation—termed “inflammaging”—plays a critical role in skin health distinct from oxidative damage or collagen breakdown [3]. This silent inflammatory process involves the sustained production of pro-inflammatory cytokines like IL-6, IL-1β, and TNF-α, which disrupt normal skin cell function without visible inflammation. Studies show that by age 50, baseline inflammatory markers in skin can increase by 2-4 fold compared to younger skin, even without visible redness or irritation [4]. This subclinical inflammation triggers matrix metalloproteinases that degrade structural proteins, impairs fibroblast function, and disrupts melanocyte regulation. Clinical research correlates these elevated inflammatory markers with uneven skin tone, reduced firmness, and compromised barrier recovery, independent of other aging mechanisms.

What This Means For You: The balanced formula in Skin Glow includes specific anti-inflammatory compounds that help regulate your skin’s immune responses without suppressing them. Several key ingredients, including bioactive peptides from Ovoderm® and phytonutrients in our formula, help maintain normal cytokine balance and support resolution pathways that terminate inflammatory cascades once they’ve served their protective purpose. This balanced approach helps preserve your skin’s natural immune function while preventing the destructive effects of chronic inflammation, supporting even tone, smooth texture, and normal recovery processes.

The Science: Research published in the International Journal of Cosmetic Science has shown that ceramides make up approximately 50% of the lipids in the skin’s outer layer (stratum corneum) [5]. These specialized lipids form the critical “mortar” between skin cells, creating a waterproof barrier. With age and environmental damage, ceramide levels can decline by up to 30%, directly correlating with increased transepidermal water loss (TEWL) and decreased barrier function. Clinical studies on wheat-derived ceramides demonstrated a 16% increase in skin hydration and a 26% reduction in skin roughness after just 15 days [6].

What This Means For You: The CERAMOSIDES™ in Skin Glow helps restore your skin’s natural barrier function, reducing moisture loss and improving resilience against environmental stressors. This strengthened barrier not only helps your skin retain hydration but also enhances your skin’s natural defense mechanisms against pollution, irritants, and other external aggressors that accelerate aging.

The Science: Research in the Journal of Dermatological Science shows that UV exposure and environmental pollutants generate reactive oxygen species (ROS) that damage skin cells and accelerate aging [7]. These free radicals break down collagen, damage cell membranes, and alter DNA expression. Studies demonstrate that skin exposed to urban pollution shows 22% more hyperpigmentation and a significant increase in wrinkle depth compared to protected skin. Antioxidants like vitamins C and E work synergistically, with vitamin C regenerating oxidized vitamin E, creating a recycling antioxidant system that provides 4x greater protection than either nutrient alone [8].

What This Means For You: The carefully balanced antioxidant complex in Skin Glow—including vitamins C, E, and selenium—creates a multi-layered defense system against free radical damage. This protection helps prevent premature collagen breakdown and cellular damage, preserving your skin’s youthful structure and appearance even when exposed to environmental stressors.

The Science: Research published in the Journal of Investigative Dermatology has revealed that the skin hosts over 1,000 bacterial species that form a complex ecosystem known as the microbiome [9]. This microbial community plays a crucial role in skin health by maintaining pH balance, strengthening barrier function, and modulating immune responses. Studies show that with age, the diversity of the skin microbiome decreases by approximately 30-40%, with particular reduction in beneficial bacteria like Lactobacillus and Bifidobacterium species [10]. This shift correlates with increased skin sensitivity, impaired barrier function, and accelerated signs of aging. Recent clinical research demonstrates that supporting a healthy skin microbiome can reduce inflammatory markers by up to 35% and improve moisture retention by 28% compared to control groups.

What This Means For You: The carefully selected ingredients in Skin Glow work in harmony with your skin’s natural microbiome, creating an environment that supports beneficial bacteria while discouraging problematic species. This balanced approach helps maintain your skin’s natural protective mechanisms, reduces sensitivity, and supports optimal barrier function. By nurturing this invisible ecosystem, Skin Glow helps preserve your skin’s natural resilience and radiance from the inside out.

The Science: A randomised, double-blind, placebo-controlled study published in Clinical, Cosmetic and Investigational Dermatology found that supplementation with eggshell membrane led to a significant improvement in skin elasticity (26% increase) and a reduction in the appearance of facial wrinkles (12% reduction) after 8 weeks [11]. Analysis of eggshell membrane shows it contains a natural matrix of collagen types I, V, and X, elastin, glycosaminoglycans, and transforming growth factor-β. This unique combination provides a complete spectrum of skin-supporting compounds in their natural ratios. Electron microscopy studies reveal that this matrix closely resembles the extracellular matrix of human skin [12].

What This Means For You: The Ovoderm® in Skin Glow provides a complete matrix of skin-supporting compounds that work together to improve elasticity and reduce the appearance of wrinkles. Unlike isolated ingredients, this natural complex delivers multiple benefits in balanced proportions as they occur in nature, supporting your skin’s structure in a way that single-ingredient supplements cannot match.

The Science: Research published in the International Journal of Biological Macromolecules has revealed that the polysaccharides in Tremella fuciformis (snow mushroom) have a unique molecular structure that offers several advantages over traditional hyaluronic acid [13]. These molecules are smaller than HA (approximately 1/10th the size), allowing for better penetration into the skin layers. Additionally, they demonstrate superior water-holding capacity, retaining moisture even in low-humidity environments. Comparative studies show that these polysaccharides maintain 87% of their hydration capacity after 24 hours, compared to 68% for standard hyaluronic acid.

What This Means For You: The GreenIuronic® in Skin Glow provides a form of hyaluronic acid with enhanced stability and moisture-retention capabilities. This translates to longer-lasting hydration throughout the day, helping your skin maintain optimal moisture levels even in challenging environments like air-conditioned offices or dry climates. The result is plumper, more resilient skin with reduced fine lines and improved texture.

The Science: Research in the American Journal of Clinical Nutrition demonstrates that micronutrients work synergistically to support skin health, with deficiencies in one nutrient often limiting the effectiveness of others [14]. For example, zinc and vitamin C work together in collagen synthesis, with zinc activating enzymes that incorporate amino acids into collagen fibers while vitamin C hydroxylates proline and lysine residues to stabilize the collagen structure. Studies show that supplementation with both nutrients increases collagen production by 35-45% more than either nutrient alone. Similarly, selenium enhances vitamin E’s antioxidant capacity by supporting glutathione peroxidase activity [15].

What This Means For You: The carefully balanced blend of micronutrients in Skin Glow—including zinc, selenium, manganese, and vitamins B6, C, and E—creates synergistic interactions that maximize skin benefits. This thoughtful formulation ensures each nutrient can perform its optimal function, supporting your skin’s natural processes more effectively than single-nutrient supplements or imbalanced formulations.

The Science: Research published in the Journal of Investigative Dermatology has identified that cellular energy production directly impacts skin renewal rates [16]. Skin cells require significant energy to divide, differentiate, and produce structural proteins like collagen and elastin. Studies show that mitochondrial function—the cell’s energy production center—declines with age by approximately 50% by age 70. This energy deficit correlates with a 30-50% slowdown in skin cell turnover and a significant reduction in protein synthesis. L-Carnitine has been shown to increase mitochondrial function by 28% in aging skin cells by facilitating fatty acid transport into mitochondria for energy production [17].

What This Means For You: The L-Carnitine in Skin Glow supports your skin cells’ energy production, helping to maintain optimal cellular function and renewal rates. This enhanced cellular energy translates to more efficient collagen production, faster skin renewal, and improved overall skin appearance. By addressing the fundamental energy needs of your skin cells, Skin Glow helps maintain a youthful renewal rate even as natural processes slow with age.

The Science: Research in the Journal of Investigative Dermatology has revealed that skin follows distinct circadian rhythms, with different processes optimised at different times of day [18]. Studies show that DNA repair and cellular regeneration peak between 10 PM and 2 AM, while skin barrier recovery is most efficient in the late afternoon. Antioxidant defense is highest in the morning and declines throughout the day. These rhythms are controlled by “clock genes” that regulate approximately 10% of the skin’s genome. Disruption of these rhythms through factors like irregular sleep patterns has been shown to accelerate skin aging by up to 30% [19].

What This Means For You: Understanding your skin’s natural rhythms can help you maximise the benefits of Skin Glow. Taking your supplement consistently at the same time each day helps maintain regular nutrient availability that supports your skin’s natural cycles. For optimal results, we recommend taking Skin Glow with breakfast to provide nutrients that support daytime protection, while the long-lasting effects ensure support for nighttime regeneration processes as well.