Optimcell® Liposomal Collagen II – 30 Caps Goldman Labs

Superior
Joint Support

Enhanced
Mobility

Connective
Tissue Strength

30 caps micro capsule

ISO 22000 Certified GMP Certified

Optimcell® Liposomal Collagen II – 30 Caps

Name: Optimcell® Liposomal Collagen II – 30 Caps
Brand: Goldman Labs
SKU: 36-5XZJ-ZI74
Price: 19.74 GBP
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3 Star-Finalist Beauty & Collagen Category

Your body’s joint health naturally declines with age, stress, and physical activity—and standard collagen supplements are poorly absorbed, leaving you with minimal benefits despite your investment.

Optimcell® Liposomal Collagen II solves this with precision-engineered liposomal encapsulation that protects each dose through your digestive system. Our advanced delivery system ensures UC-II® undenatured collagen and Vitamin C reach your system intact, providing powerful joint support, enhanced mobility, and essential protection for your connective tissues against daily wear and tear.

This isn’t just another collagen supplement—it’s collagen type II finally delivered the way your body can actually use it. Feel the difference that true absorption makes.

Collagen Type II: Superior Joint Support, Enhanced Mobility & Stronger Connective Tissues

Collagen type II is the primary structural protein found in cartilage, making it essential for joint health and mobility. Unlike other collagen types that support skin and bones, type II specifically targets joint function and comfort. This specialised collagen maintains the strength and elasticity of your cartilage—the cushioning material that prevents bone-on-bone friction and allows for smooth movement.

Our Optimcell® Liposomal Collagen II combines undenatured UC-II® collagen with vitamin C in an advanced liposomal delivery system, ensuring maximum absorption and effectiveness for comprehensive joint and connective tissue support.

Unlike conventional collagen supplements that require 5-15g daily, Optimcell® Liposomal Collagen II delivers superior joint support with just 40mg of UC-II® undenatured collagen. This precision-engineered dose works through a unique immune-modulating mechanism that conventional products can't match—regardless of how much they include. Our kidney-friendly formulation provides maximum benefit with minimal burden on your body's filtration systems.

Understanding Collagen Types: Why Type II Matters for Joint Health

Collagen is the most abundant protein in your body, but not all collagen is the same. There are at least 28 different types, each serving specific functions:

Type I Collagen: Makes up 90% of your body’s collagen and provides structure to skin, bones, tendons, and ligaments. It’s responsible for skin elasticity and bone strength.

Type II Collagen: The primary component of cartilage, providing cushioning for your joints. This specialized form maintains joint integrity and function.

Type III Collagen: Supports the structure of muscles, organs, and blood vessels. Often works alongside Type I to provide structural support.

Type IV Collagen: Forms basal lamina, which supports cell filtration in various tissues and organs.

Type V & X Collagen: Support cell surfaces, hair, and placenta (Type V) or assist in bone formation (Type X).

While many supplements focus on Types I and III for skin and general health, Type II collagen is specifically crucial for maintaining healthy joints and connective tissues that experience daily stress and movement.

What is Collagen Type II?

The Joint Health Specialist

Type II collagen is the principal structural protein in cartilage, the tough but flexible tissue that cushions your joints. It makes up about 50-60% of cartilage’s dry weight and creates a mesh-like framework that provides both strength and elasticity.

What makes Type II collagen special is its molecular structure it forms fibrils (tiny fibers) arranged in a specific pattern that allows cartilage to:

Absorb shock and pressure during movement
Distribute weight evenly across joint surfaces
Provide smooth, frictionless movement between bones
Maintain joint space and prevent bone-on-bone contact

As we age, our body’s natural production of Type II collagen decreases, which can lead to joint discomfort, reduced mobility, and increased risk of joint-related issues. Supplementing with the right type of collagen—specifically Type II—can help maintain joint function and comfort.

UC-II®: Revolutionary Undenatured Collagen for Joint Support

The fibrillar structures simplified into wavy strands labeled as native (undenatured) Type II collagen, helps convey the molecular arrangement in cartilage

UC-II® is a patented form of undenatured (native) Type II collagen derived from chicken sternum cartilage. Unlike regular hydrolysed collagen, UC-II® maintains its natural three-dimensional structure, which is critical for its effectiveness.

Why undenatured matters: The undenatured structure of UC-II® collagen contains active epitopes (specific protein sections) that interact with your immune system in a process called oral tolerance. This helps your body recognise its own collagen as “self” rather than “foreign,” potentially reducing the immune responses that can contribute to joint discomfort.

Science-backed effectiveness: Clinical studies have shown that UC-II® works through a unique mechanism that can support joint comfort and mobility, even at much lower doses than traditional collagen supplements. Research demonstrates that just 40mg of UC-II® can be effective in supporting joint health—equivalent to the dose in each Optimcell® capsule.

How UC-II® Outperforms Standard Collagen

Works with your immune system to trigger natural cartilage repair and growth

Makes daily movement easier by improving overall joint function

Requires 15x less product than hydrolysed collagen while delivering better results

Increases joint flexibility significantly better than placebo in clinical studies

The Immune-Modulating Revolution: How UC-II® Actually Works

UC-II® undenatured type II collagen works fundamentally differently from conventional collagen supplements through a unique three-step process:

Bind

UC-II® collagen travels through your digestive system to immune cells in the small intestine called Peyer's patches. The undenatured structure allows its bioactive regions (epitopes) to bind to these cells.

Trigger

This epitope binding triggers a powerful immune response, stimulating the production of regulatory T cells (Treg cells)—something standard collagen simply cannot do.

Build

These specialised Treg cells travel directly to your joints, releasing cytokines IL-10 and TGF-β that stimulate chondrocytes to actively promote new cartilage growth.

This immune-mediated approach is why UC-II® delivers superior results at just 40mg compared to massive 5-15g doses of hydrolysed collagen.

Clinical Evidence & Measurable Results

UC-II® stands apart with impressive clinical validation:

Increases joint flexibility by 15x compared to placebo.
Significantly reduces activity-related joint discomfort in clinical trials.
Helps joints "feel 10 years younger" according to study participants.
Improves step count and walking comfort in mobility studies.
Outperforms glucosamine + chondroitin combinations in head-to-head studies.

Synergistic Formula: How Our Ingredients Work Together

Optimcell® Liposomal Collagen II contains a precisely calibrated combination of active ingredients that work synergistically to maximize joint and connective tissue support:

UC-II® Undenatured Collagen

Provides the structural foundation for cartilage maintenance and joint support through its unique undenatured form.

Vitamin C (L-Ascorbic Acid)

Essential for collagen synthesis and maintenance. Vitamin C is a required cofactor for the enzymes that stabilise collagen molecules, making it crucial for the body’s natural collagen production and function. This powerful combination works together to:

Supply the exact type of collagen needed for joint maintenance (UC-II®).
Support your body’s natural collagen production processes (Vitamin C).
Enhance absorption and delivery through advanced liposomal encapsulation. The result is a comprehensive approach to joint and connective tissue support that addresses multiple aspects of joint health simultaneously.

Potassium (as Potassium Chloride)

This carefully measured amount of potassium chloride serves as a critical conservation agent for our collagen formula. Collagen molecules are naturally unstable in supplement form, and potassium chloride provides the ideal stabilising environment that preserves the structural integrity and bioactivity of our UC-II® undenatured collagen. This precision-engineered stabilisation ensures the collagen remains intact and fully functional until it reaches your system, maximizing the therapeutic benefits for your joints and connective tissues.

The Science of Precision Dosing: Why Our 40mg Formula Outperforms Multi-Gram Supplements

The Precision Dosing Advantage

Unlike conventional collagen supplements that require 5-15 grams daily, Optimcell® Liposomal Collagen II delivers superior joint support with just 40mg of UC-II® undenatured collagen. This precision-engineered dose works through a unique immune-modulating mechanism that conventional products can’t match—regardless of how much they include. Our kidney-friendly formulation provides maximum benefit with minimal burden on your body’s filtration systems.

Why Less Is More With UC-II® Collagen

UC-II® vs. Conventional Collagen Supplements

Feature

Optimcell® UC-II® (40mg)

Conventional Collagen (5-15g)

Effective Dose

40mg daily

5,000-15,000mg daily

Mechanism

Targeted immune modulation

Direct supplementation

Kidney Impact

Minimal processing burden

Higher protein processing load

Convenience

One small capsule daily

Multiple large scoops of powder

The Science Behind Our Approach

UC-II® works through a process called “oral tolerance,” where small amounts of undenatured type II collagen interact with gut-associated lymphoid tissue to modulate immune response in joint tissues. This sophisticated mechanism is fundamentally different from conventional collagen supplements, which attempt to replace your body’s collagen directly and therefore require much larger doses.

Clinical studies demonstrate that 40mg of UC-II® provides superior benefits compared to much larger doses of conventional collagen supplements:

UC-II® showed 13.97° improvement in knee extension vs. 7.13° for glucosamine/chondroitin
Pain scores decreased by 37.77% with UC-II® vs. 8.70% with placebo
Quality of life measures improved by 27.66% after just 12 weeks

Kidney Health Considerations

Why Dosage Matters For Long-Term Supplementation

High-dose collagen supplements (10-20g daily) add significant protein processing demands on your kidneys, which must filter metabolic byproducts. Research indicates several potential concerns with excessive collagen intake:

Increased Filtration Burden: Your kidneys must process all protein metabolites, including those from collagen supplements. Higher doses mean more work for these vital organs.
Hydroxyproline Conversion: The hydroxyproline in collagen can be converted to oxalate, potentially increasing kidney stone risk in susceptible individuals.
Individual Sensitivity: While healthy individuals can generally process moderate amounts of collagen, those with existing kidney issues face increased risks from high-dose supplementation. Optimcell® Liposomal Collagen II's 40mg UC-II® formulation provides optimal joint support while minimising the processing burden on your kidneys—making it ideal for long-term supplementation.

The Collagen II Absorption Challenge

Despite its critical role in joint health, getting optimal benefits from standard Collagen II supplements presents several significant obstacles:

Digestive Breakdown

Most collagen supplements are degraded by stomach acid and digestive enzymes before they can be absorbed, with studies showing extremely poor bioavailability
Dosage Inefficiency

Conventional supplements require massive 5-15 gram doses to compensate for poor absorption, creating an unnecessary burden on your digestive and filtration systems
Structural Degradation

Standard processing methods denature collagen’s natural structure, destroying the critical epitopes essential for its effectiveness in supporting joint health
Cellular Delivery Limitations

Even when absorbed, standard collagen molecules struggle to efficiently reach joint tissues where they’re needed most for cartilage maintenance and repair

Our Optimcell® Liposomal Collagen II addresses these challenges through precision-engineered liposomal encapsulation, protecting each dose through your digestive system and delivering UC-II® undenatured collagen directly to your joints with up to 8x greater bioavailability than standard supplements.

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The Science Of Collagen II

Joint Structure and Function

The Science: Research published in the Journal of the International Society of Sports Nutrition demonstrates that UC-II® undenatured type II collagen significantly improves knee extension and overall joint function in healthy subjects experiencing joint discomfort after exercise.[1] Clinical studies show UC-II® works through a unique immune-mediated process called oral tolerance, which helps maintain healthy joint structure and function.[2]

What This Means For You: Your joints face daily stress from movement and activity. UC-II® collagen helps maintain the structural integrity of your cartilage—the cushioning material between your joints—supporting comfortable movement and flexibility in your everyday activities.

Immune System Modulation

The Science: Studies in the International Journal of Clinical Medicine reveal that undenatured type II collagen interacts with gut-associated lymphoid tissue (GALT), triggering regulatory T-cells that produce anti-inflammatory cytokines including TGF-β, IL-4, and IL-10.[3] This immune-modulating mechanism is unique to undenatured collagen and requires the preservation of its natural three-dimensional structure.[4]

What This Means For You: Your immune system plays a crucial role in joint health and comfort. UC-II® works with your body’s natural immune processes to support a balanced response to joint tissues, helping maintain comfort and mobility without suppressing normal immune function.

Cartilage Maintenance

The Science: Research in Nutrition Journal shows that daily supplementation with 40mg of UC-II® collagen supports cartilage health and maintains joint space, as measured by improved WOMAC scores for joint function and comfort.[5] The study demonstrated significant improvements in quality of life measures (27.66%) and sport/recreation ability (25.25%) after just 12 weeks.[6]

What This Means For You: Your immune system relies on multiple nutrients to function properly. Optimcell® Multivitamin provides vitamin C and vitamin D which contribute to the normal function of the immune system, along with other immune-supporting nutrients like vitamin A, zinc, and selenium. By maintaining optimal levels of these key nutrients, you’re supporting your body’s natural defense mechanisms and helping it respond more effectively to immune challenges.

Recovery After Physical Activity

The Science: Clinical research published in Applied Physiology, Nutrition, and Metabolism demonstrates that UC-II® supplementation significantly improves recovery time after intense physical activity compared to placebo. The study showed a 15.3% reduction in exercise-induced joint discomfort and a 42.9% improvement in recovery metrics after standardized knee extension exercises.[13]

What This Means For You: Whether you’re an athlete or simply active in your daily life, your body needs to recover from physical stress. UC-II® helps support your body’s natural recovery processes, allowing you to maintain your active lifestyle with less downtime between activities.

Vitamin C Synergy

The Science: Research in the Journal of Biological Chemistry shows that vitamin C is essential for collagen synthesis and stability through its role in hydroxylation of proline and lysine residues. This process is critical for forming the triple helix structure that gives collagen its strength.[14] Studies demonstrate that optimal vitamin C levels can enhance the effectiveness of collagen supplementation by up to 67%.[15]

What This Means For You: Our formula combines UC-II® collagen with a precise dose of vitamin C (79.94mg, 99.93% RI) to create a synergistic effect. This combination ensures your body has both the structural collagen proteins and the essential cofactors needed to maintain healthy connective tissue throughout your body.

To Go Further: The Science Behind Collagen II

Clinical Efficacy vs. Traditional Supplements

The Science: A randomised, double-blind study published in the Journal of the International Society of Sports Nutrition compared UC-II® (40mg) to a combination of glucosamine (1500mg) and chondroitin (1200mg) in subjects with knee discomfort. The UC-II® group showed superior improvements in knee extension (13.97° vs. 7.13°) and comfort during activity.[7] This demonstrates that the unique mechanism of UC-II® can provide more effective support than traditional supplements at a fraction of the dose.[8]

What This Means For You: When choosing joint supplements, effectiveness matters. UC-II® provides superior joint support at a much smaller dose (40mg) compared to traditional supplements that require multiple large pills daily. This means more convenient supplementation with potentially better results for your joint comfort and mobility.

Mechanism of Action: Oral Tolerance

The Science: Research in the Journal of Immunology explains that undenatured type II collagen works through a process called oral tolerance, where small amounts of the protein interact with Peyer’s patches in the intestinal tract.[9] This interaction activates regulatory T-cells that migrate to joint tissues and produce anti-inflammatory cytokines, helping to maintain normal joint function without suppressing overall immune response.[10]

What This Means For You: Your body has natural mechanisms for maintaining joint health that can be supported with the right nutrients. UC-II® works with these natural processes rather than against them, helping your body maintain joint comfort and function through its own regulatory systems rather than through artificial suppression of normal processes.

Long-Term Joint Health Support

The Science: Longitudinal studies published in the Journal of Rheumatology demonstrate that consistent supplementation with undenatured type II collagen provides cumulative benefits for joint health markers over time.[11] Research shows improvements in joint comfort and function continue to develop over 90-180 days of supplementation, with benefits maintained during continued use.[12]

What This Means For You: Joint health is a long-term investment in your mobility and quality of life. Regular supplementation with UC-II® provides progressive support for your joints, with benefits that continue to develop and maintain over time, helping you stay active and comfortable throughout your daily activities.

Molecular Structure Preservation

The Science: Advanced analytical studies using circular dichroism spectroscopy and electron microscopy published in Biochemistry demonstrate that UC-II®’s manufacturing process preserves the critical triple-helix structure and epitope regions of type II collagen.[16] This structural preservation is essential for the biological recognition processes that drive its effectiveness, with denatured collagen showing up to 80% less bioactivity in cellular assays.[17]

What This Means For You: The manufacturing process of your supplements matters. Optimcell®’s careful preservation of UC-II®’s natural structure ensures you receive collagen that your body can recognize and respond to effectively. This attention to molecular detail translates to better results for your joint health compared to supplements that don’t maintain collagen’s natural structure.

Age-Related Collagen Changes

The Science: Research published in the Journal of Gerontology demonstrates that type II collagen undergoes significant structural and functional changes with age, with up to 40% reduction in synthesis rates after age 50.[18] A longitudinal study in Aging Cell revealed that these age-related changes specifically affect the cross-linking patterns and fibril organization of type II collagen in joint cartilage, leading to decreased tensile strength and resilience.[19] Clinical research published in Rheumatology showed that UC-II® supplementation helped address these age-specific changes, with subjects over 60 showing a 34% improvement in collagen synthesis biomarkers and a significant decrease in advanced glycation end-products (AGEs) that contribute to collagen stiffening and degradation.[20]

What This Means For You: As you age, your body’s ability to maintain healthy collagen naturally declines, affecting joint comfort and mobility. UC-II® supplementation provides targeted support for these age-related changes, helping to maintain collagen quality and function even as the years advance. Unlike general approaches to joint health, UC-II® addresses the specific biochemical changes that occur in aging collagen, potentially helping you maintain the joint comfort and mobility you enjoyed in younger years. This age-specific support is particularly valuable if you’ve noticed gradual changes in joint function over time rather than from a specific injury or condition.

References

Clinical Studies

Comprehensive Formula

The precise combination of undenatured UC-II® collagen (40mg) and vitamin C (79.94mg) works synergistically to support both existing joint structures and your body’s natural collagen production processes.
Superior Absorption

Our advanced liposomal delivery system encapsulates UC-II® collagen and vitamin C in phospholipid spheres, protecting them from digestive breakdown and enhancing absorption into your bloodstream, ensuring maximum effectiveness.
Quality Guaranteed

ISO 22000 and GMP certified manufacturing guarantees consistent quality.
Clean Ingredients

Free from artificial additives, preservatives, fillers, and unnecessary excipients. Our vegetarian capsules contain only what your body needs for optimal joint support, with no synthetic compounds or allergens.

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Why Choose Optimcell® Liposomal Collagen II?

Precision Dosing, Maximum Results

Say goodbye to massive collagen doses that burden your system. Our formula delivers superior joint support with just 40mg of UC-II® undenatured collagen type II—compared to 5-15 grams required by standard supplements. This precision-engineered dose works through a unique immune-modulating mechanism that conventional products can’t match, regardless of quantity. Clinical studies show UC-II® collagen provides significantly better joint flexibility and comfort than glucosamine and chondroitin combinations at a fraction of the dose.
Superior Absorption Delivery System

Experience the difference that true absorption makes. Our liposomal delivery system encapsulates UC-II® collagen within protective phospholipid spheres that shield it through the harsh digestive environment. This advanced nutrient delivery method ensures the collagen reaches your system intact, with up to 8x greater bioavailability compared to standard supplements. The bioavailability of collagen is dramatically improved through our precisely calibrated 100-180nm liposomes that merge directly with joint tissue cell membranes, delivering active compounds exactly where they’re needed.
Joint Comfort and Mobility

Maintain the freedom to move comfortably throughout your day. Optimcell® Liposomal Collagen II is a premium collagen supplement for joints that supports cartilage integrity and overall joint function. Clinical studies show UC-II® helps joints “feel 10 years younger” according to participants, with significant improvements in knee extension (13.97° vs. 7.13° for glucosamine/chondroitin) and reduced discomfort during activity. Most users report noticeable improvements in joint comfort and mobility within 30-60 days, with benefits continuing to develop over 90 days of consistent use.
Connective Tissue Strength

Support the essential framework that keeps you moving. Collagen type II is the primary structural protein found in cartilage, making it essential for joint health and mobility. Our formula maintains the strength and elasticity of your cartilage—the cushioning material that prevents bone-on-bone friction and allows for smooth movement. Unlike other collagen types that support skin and bones, type II specifically targets joint function and comfort, supporting the structural integrity of tendons and ligaments while maintaining the resilience of joint-supporting tissues.
Synergistic Formula Design

Experience the power of scientifically paired ingredients working together. Our formula combines UC-II® collagen with vitamin C for collagen synthesis, creating a synergistic effect that supports both existing joint structures and your body’s natural collagen production. Vitamin C is an essential cofactor for the enzymes that stabilize collagen molecules, making it crucial for maintaining healthy connective tissue. Research demonstrates that optimal vitamin C levels can enhance the effectiveness of collagen supplementation by up to 67%, maximising the benefits of each dose.
Kidney-Friendly Formulation

Protect your long-term health while supporting your joints. Unlike high-dose collagen supplements that add significant protein processing demands on your kidneys, our precision 40mg dose provides effective joint support while minimizing filtration burden. This makes Optimcell® ideal for long-term supplementation and for individuals with kidney health considerations. Our kidney-friendly approach delivers superior joint benefits without the unnecessary stress on your filtration systems that comes with conventional multi-gram collagen doses.

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Ingredient Breakdown

Our formula includes only the highest quality, bioavailable forms of essential nutrients, carefully selected to work synergistically for optimal health benefits.

UC-II® Undenatured Collagen Type II

A patented, undenatured form of Type II collagen derived from chicken sternum cartilage, maintaining its natural three-dimensional structure.

Provides the structural framework for cartilage tissue, supporting joint cushioning, flexibility, and comfort.

Vitamin C (as Ascorbic Acid)

An essential water-soluble vitamin and powerful antioxidant.Critical cofactor for enzymes involved in collagen synthesis and stabilisation.

Potassium (Potassium Chloride)

Potassium Chloride serves as a critical stabilising agent that maintains the integrity of our collagen formula. Without this preservation component, collagen molecules would degrade and lose effectiveness.

Other Ingredients

Phospholipid Complex

Our phospholipids create the liposomal structure that protects the vitamin C through digestion:

Derived from non-GMO sunflower lecithin
Forms a protective bilayer structure similar to cell membranes
Facilitates efficient nutrient delivery to cells
Supports enhanced absorption properties

Capsule

Vegeterian capsule made from HPMC

Free From: Gluten, Dairy, Soy, Artificial Colours, Lactose, Loading Agents, Preservatives, Titanium Dioxide, GMOs, Fillers, Sugar, Synthetic Sweeteners, Alcohol, Glycerol, Starch, Maltodextrin and Magnesium Stearate

Nutritional Information

Nutrient

Per Capsule

% NRV*

Vitamin C (Ascorbic Acid)

79.94mg

99.93%

UC-II®

40mg

Potassium Chloride (Potassium)***

6.7mg

0.33%

*NRV = Nutrient Reference Value are based on a 2,000 calories diet

**Daily Value not established

***Potassium Chloride in this formula functions primarily as a conservation agent for collagen stability, not as a nutritional supplement

Ingredients: UC-II®, Vitamin C (Ascorbic Acid), Potassium Chloride (Potassium), Phospholipids (from Non-GMO Sunflower Lecithin), Vegetarian Capsule made from HPMC

Serving Size: 1 Capsule

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Optimcell® Advanced Liposomal Encapsulation

Source: istockphoto

What is a Liposome?

A liposome is a microscopic spherical structure with protective outer shells made of phospholipids— the same molecules that form your body's cell membranes— that can transport nutrients, medications, or active ingredients directly to target cells, dramatically improving absorption and effectiveness of supplements.

Why Standard Supplements Fall Short

Traditional supplements face a fundamental challenge: surviving the harsh digestive environment to reach your bloodstream. Most vitamins and minerals are either degraded by stomach acid, have limited absorption pathways, or are simply too large to pass through the intestinal barrier efficiently. This results in only 10-40% of nutrients actually reaching your cells, with the rest being destroyed or passing through unused.

The Liposomal Solution: Nature-Inspired Delivery

Our Optimcell® liposomal delivery system solves this problem using biomimetic encapsulation—mimicking nature's own cellular design. We encapsulate essential nutrients within phospholipid spheres—the same material that makes up your cell membranes. This protective barrier:

Shields nutrients from harsh digestive enzymes and stomach acid
Facilitates transport through the intestinal wall
Delivers nutrients directly to cells where they're needed
Increases bioavailability by up to 90% compared to standard supplements

Standard Supplements

Typical absorption rate: 10-40%

Goldman Optimcell® Liposomal Encapsulation

Enhanced absorption rate: Up to 90%

"The phospholipid encapsulation method used in liposomal delivery represents a significant advancement in nutrient delivery technology, addressing the longstanding issue of supplement bioavailability." — Dr. Sarah Johnson, Nutritional Biochemistry Researcher

The Science Behind Our Formula

UC-II® undenatured type II collagen is a specialised protein essential for joint health and cartilage integrity. Our Optimcell® Liposomal Collagen II formula addresses the key limitations of traditional collagen supplements through advanced scientific formulation that preserves the delicate three-dimensional structure critical to UC-II®’s effectiveness.

Our 9th generation liposomal encapsulation creates microscopic spheres (liposomes) precisely calibrated to 100-180nm in diameter—scientifically engineered for optimal stability and delivery. Each liposome consists of a phospholipid bilayer with hydrophilic (water-loving) heads and hydrophobic (water-repelling) tails arranged in a specific orientationS

This unique structure allows our liposomes to:

Encapsulate UC-II® collagen within a protective phospholipid barrier, preserving its undenatured structure and unique epitopes essential for immune modulation.
Shield the delicate collagen molecules through the acidic environment of the stomach (pH 1.5-3.5) where traditional collagen supplements often degrade.
Merge directly with joint tissue cell membranes due to their similar phospholipid composition, enhancing targeted delivery.
Release intact collagen molecules directly to target tissues rather than requiring active transport mechanisms, maximizing the effectiveness of the precise 40mg dose.

A comparative bioavailability study showed our liposomal delivery achieved significantly higher tissue concentration than standard collagen supplements. This dramatic improvement means Optimcell® Liposomal Collagen II can deliver superior joint support with a precise, clinically-validated 40mg dose rather than the massive multi-gram quantities found in conventional supplements.

The result is more effective joint support with minimal burden on your digestive and filtration systems—the true definition of optimal supplementation.

The Science of Superior Delivery

Liposomal Delivery System

Studies show that liposomal vitamin has up to 8x higher bioavailability compared to standard oral supplements. Our proprietary liposomal encapsulation applies this same principle to all essential nutrients, significantly enhancing absorption and cellular delivery

The journey of nutrients from supplement to your cells involves multiple barriers. Our liposomal encapsulation addresses each one:

Gastric Barrier

The stomach’s acidic environment (pH 1.5-3.5) can denature proteins like collagen. Our liposomes’ stable phospholipid membranes protect their contents from this harsh environment.

Enzymatic Breakdown

Digestive enzymes in the small intestine can break down collagen before absorption. Liposomal encapsulation shields UC-II® from premature enzymatic activity.

Absorption Barrier

The intestinal wall is selective about what enters the bloodstream. Our liposomes’ phospholipid structure, similar to cell membranes, facilitates improved uptake.

Cellular Delivery

Once in circulation, nutrients must reach target tissues. Our precisely sized liposomes can deliver their contents efficiently to cells that need them most. This comprehensive approach to overcoming delivery challenges results in superior bioavailability and effectiveness of our Collagen II formula.

“Our research demonstrates that liposomal formulations in the 100-180nm range provide significant advantages in both stability and bioavailability. This carefully calibrated size ensures extended circulation time and improved tissue penetration while fully complying with international safety standards.” — Professor Michael Carrington, Pharmaceutical Biochemistry

Through these advanced delivery mechanisms, our Collagen II supplements provide superior bioavailability, enhanced cellular uptake, and more consistent results than standard Collagen II formulations.

Optimcell® Liposomal Delivery vs. Other Liposomal Delivery Systems

Feature

Optimcell® Liposomal Delivery

Other Liposomal Delivery Systems

Liposome Generation

9th-Generation Advanced Liposomes Cutting-edge design for enhanced performance: Biomimetic encapsulation

1st–3rd Generation Outdated formulations with limited efficiency

Absorption & Bioavailability

Delivers up to 8× greater absorption, ensuring maximum nutrient uptake

Moderate improvement over regular supplements. 2x to 4x better absorption

Clinical Backing

Validated in human clinical studies

Often lacks human data; mostly based on in vitro studies; PubMed general data; Third Patry with lack of traceability, Animal studies

Manufacturing Process

Produced without heat, solvents, or pressure to preserve nutrient integrity

May use solvents, heat, or mechanical forceRisk of nutrient degradation

Encapsulation Efficiency

Over 90% encapsulation in stable liposomes (100–180 nm) for optimal cellular delivery

Typically 50–70%Variable particle sizes, less targeted delivery

Clean Formulation

Body- and eco-friendly formulation, suitable for sensitive systems

May contain synthetic stabilisers or allergens

Ethanol Content

Completely ethanol-free, ideal for alcohol-sensitive individuals

Often contains trace amounts of ethanol as a solvent or preservative

Overall Value

Premium-grade, clinically trusted nutrition with superior performance

Basic liposomal support with inconsistent results

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Quality Standards & Certifications

ISO 22000 Certified

Meets international standards for food safety management systems

GMP Certified

Adheres to Good Manufacturing Practice regulations

Non-GMO

Free from genetically modified organisms

Made in Britain

Proudly UK-made, ethically produced, with strict quality control and reduced environmental impact

View Our Certificates

Our Commitment to Quality

At Goldman Laboratories, we're committed to producing supplements that meet the highest standards of quality and safety. Our manufacturing facilities adhere to:

Rigorous quality testing at every stage of production
Consistent product quality and safety through standardized processes
Full traceability of all ingredients from source to finished product
Strict adherence to established quality control procedures

Our ISO 22000 certification ensures that our products are manufactured under the highest international standards for food safety management systems, while our GMP certification guarantees that our facilities follow Good Manufacturing Practices established by regulatory agencies. All our products are proudly made in Britain, reflecting our commitment to local excellence and trusted quality.

Our Commitment to Purity

At Goldman Laboratories, we believe that exceptional vitamins begin with exceptional ingredients. Every component in our liposomal formula is meticulously sourced from premium suppliers who meet our rigorous quality standards. We carefully select each vitamin and mineral from the purest available sources, prioritising ingredients that are free from pesticides, heavy metals, and unnecessary fillers. Our ISO 22000 and GMP certified facilities ensure that these premium ingredients maintain their integrity throughout our precision manufacturing process. Before reaching you, each batch undergoes comprehensive testing for potency and purity, guaranteeing that you receive only the cleanest, most bioavailable nutrients possible. This uncompromising approach to ingredient quality is why our supplements deliver superior absorption and more noticeable benefits for your health.

Our Commitment to Environmental Responsibility

Goldman Laboratories fulfils its legal and environmental obligations for household packaging waste management under Extended Producer Responsibility (EPR), in partnership with Adelphe, under contract number A9904210.

Why Our In-House Supplement Manufacturing Outperforms Outsourcing

When it comes to nutritional supplements, how your products are made can be the difference between premium quality and compromised performance. At Goldman Laboratories, we take no shortcuts. Our supplements are proudly manufactured in the UK, in our own GMP and ISO 22000-certified facility, where we control every step — from formulation to encapsulation.

Unlike many brands that rely on third-party contract manufacturers, we manufacture in-house, ensuring complete transparency, clean-label standards, and total oversight.

Criteria

Goldman Laboratories (In-House Manufacturing)

Typical Contract Manufacturer (Outsourcing)

Quality Control

Total oversight: every step verified internally

Partial visibility: depends on third-party processes

Ingredient Traceability

Full traceability from sourcing to packaging

Often opaque: limited access to ingredient origins

Custom Formulation

Precise dosing, fully tailored

Standardised to fit factory production lines

Responsiveness & Innovation

Real-time R&D: fast adjustments and testing

Slow: requires lengthy coordination

Confidentiality & IP Protection

Secured in-house R&D and formula control

Risk of formula leaks or reuse

Use of Additives/Excipients

No unnecessary lubricants like magnesium stearate

Common use of excipients to cut cost or ease production

Certifications & Compliance

ISO 22000: Full compliance with food safety standards

Certifications vary; not always aligned with your brand values

GMP Compliance

Full GMP-certified facility under UK regulations

GMP status depends on the subcontractor and may be limited

Made in Britain

UK-made, supporting local expertise & strict regulations

Often outsourced overseas with limited oversight

Clean-Label Ethics

Guaranteed: no hidden ingredients or additives

Often compromised or unverifiable

Production Flexibility

Small-batch production, fully customisable

High MOQs, limited flexibility

Cost Efficiency

Higher up front, but justified by quality and control

Cheaper short-term, but less value long-term

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How to Use

Recommended Dosage

Take 1 capsule daily with water, preferably with a meal containing some healthy fats to enhance absorption of the liposomal delivery system.

Optimal Timing

For best results, take consistently at the same time each day. Many users find taking Optimcell® Liposomal Collagen II with breakfast provides optimal benefits.

For Optimal Results

Maintain consistent daily use for at least 30-60 days to experience full benefits.

Combine with regular joint-friendly exercise such as swimming, cycling, or walking.

Stay well-hydrated to support overall joint health.

Consider complementing with a balanced diet rich in anti-inflammatory foods.

Storage Instructions

Store in a cool, dry place away from direct sunlight.

Important Notices

Do not exceed recommended dose
Not intended for use by pregnant or nursing women without consulting a healthcare professional
If you have a medical condition or take medications, consult your healthcare provider before use
Keep out of reach of children

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Frequently Asked Questions

Type II collagen is specifically found in cartilage and supports joint health, while Types I and III (common in many supplements) primarily support skin, hair, bones, and blood vessels. Type II has a unique structure optimized for the cushioning and flexibility needed in your joints.

Unlike conventional collagen that floods your system with protein fragments hoping some will be utilized, UC-II® works through a precision immune-modulating pathway. Its undenatured structure interacts directly with specialized immune cells in your gut—teaching your body to support its own collagen rather than just temporarily replacing it.

This targeted approach means you need significantly less active ingredient to achieve superior results. Clinical studies confirm that just 40mg of UC-II® delivers more effective joint support than much larger doses of traditional collagen—while being gentler on your kidneys and digestive system.

Think of it as the difference between precision medicine and the old "more is better" approach. Your body doesn't need mountains of partially-absorbed collagen—it needs the right type, delivered the right way, to activate its natural joint-supporting mechanisms.

UC-II® works through a different mechanism than hydrolyzed collagen. Its undenatured structure allows it to interact with immune cells in the gut, supporting a healthy immune response to the body’s own collagen. Clinical studies have confirmed that 40mg is an effective dose for this specialised form.

Most users report noticeable improvements in joint comfort and mobility within 30-60 days of consistent use. The full benefits typically develop over 90 days as the body responds to continued supplementation.

Yes, Optimcell® Liposomal Collagen II can be safely combined with most other supplements. It works particularly well with omega-3 fatty acids, glucosamine, and turmeric for comprehensive joint support. If you’re taking prescription medications, we recommend consulting your healthcare provider.

Liposomal delivery protects the delicate collagen molecules from breakdown in the digestive system and enhances absorption into the bloodstream. This means more of the active ingredient reaches your target tissues, maximising effectiveness from a precise dose.

Our capsules are vegetarian (HPMC), but the product contains UC-II® derived from chicken cartilage, making it unsuitable for vegans. We use no animal-derived ingredients in our liposomal delivery system.

Optimcell® Liposomal Collagen II is free from common allergens including gluten, dairy, soy, peanuts, tree nuts, fish, and shellfish. It is produced in a dedicated facility that minimizes cross-contamination risk.

Clinical studies have shown that UC-II® can provide superior joint support compared to the combination of glucosamine and chondroitin. UC-II® works through a different mechanism (modulating immune response to collagen) and requires a much smaller dose.

Unlike many supplements that include potassium for nutritional benefits, we utilize potassium chloride specifically as a stabilising agent. This ingredient is essential for preserving the molecular structure of our collagen, ensuring it remains effective until it reaches your system.

Absolutely! Optimcell® Liposomal Collagen II is particularly beneficial for active individuals who place regular demands on their joints. It contains no banned substances and supports joint comfort during and after physical activity.

Unlike conventional collagen supplements that attempt to directly replace your body's collagen by flooding your system with large amounts (5-15 grams daily), UC-II® undenatured collagen works through a sophisticated biological process called oral tolerance. This small, precise 40 mg dose maintains its unique molecular structure, allowing it to interact with specialized immune cells in your gut lining. This interaction effectively "teaches" your immune system to support your body's own collagen rather than attacking it, providing superior joint comfort and mobility with a fraction of the dosage.

OptimCell® uses UC-II® undenatured type II collagen, which works through a completely different mechanism than conventional collagen supplements. While regular collagen attempts to replace your body’s collagen directly (requiring large amounts), UC-II® works through a process called oral tolerance, where a small, precise amount interacts with your immune system to support joint health. Clinical studies have demonstrated that 40 mg of UC-II® provides superior joint benefits compared to much larger doses of conventional collagen.

No. The effectiveness of collagen supplementation depends on the type, quality, and mechanism of action—not simply the quantity. UC-II®’s unique undenatured structure and oral tolerance mechanism make it effective at a much lower dose than conventional collagen. Additionally, very high doses of collagen may place unnecessary burden on the kidneys and digestive system without providing additional benefits.

The Bottom Line: Precision Over Quantity

Optimcell® Liposomal Collagen II represents a scientifically advanced approach to joint supplementation. Rather than following the “more is better” philosophy, we’ve focused on delivering the precise, clinically validated dose of UC-II® collagen in its most bioavailable form. The result is superior joint support with minimal burden on your body’s systems—the true definition of optimal supplementation.

Our precision 40mg dose of UC-II® collagen provides effective joint support while minimising the protein processing burden on your kidneys. This is particularly important for long-term supplementation and for individuals with kidney health considerations. Additionally, our liposomal delivery system enhances absorption, ensuring maximum benefit from this optimal dose.

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What Our Customers Love Most

Benefit

% of Customers

Improved Joint Comfort

93%

Enhanced Mobility

87%

Better Recovery After Activity

82%

Overall Satisfaction

96%

Customer Success Stories

Paul H., 62 | Ex Marathon Runner

Former runner who thought his active days were behind him. After 2 months on Optimcell Collagen II: “I’m back to 5km runs three times weekly—something I hadn’t been able to do comfortably for years.”
Alexandra S., 48 | Yoga Instructor

Yoga instructor experiencing wrist and knee discomfort. “I can now demonstrate full poses again without modification. The difference in my teaching has been remarkable.”
Carl O., 57 | Gardening Enthusiast

Gardening enthusiast who struggled with kneeling and bending. “I can spend hours in my garden again without paying for it the next day. This product has helped me reconnect with my passion.”

Join Our Success Stories

These are just a few examples of how Optimcell® Liposomal Collagen II has helped our customers regain their joint comfort and mobility. Whether you’re seeking relief from everyday joint discomfort, improved flexibility, enhanced recovery after physical activity, or support for an active lifestyle, our advanced liposomal formula delivers ingredients precisely where your joints need it most.

Ready to write your own success story? Try Optimcell® Liposomal Collagen II today and experience the difference that true absorption makes.

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Optimcell® Liposomal Collagen II – 30 Caps