Omega-3 Fatty Acids and Testosterone: What Men Over 60 Need to Know

Omega-3 Fatty Acids and Testosterone: What Men Over 60 Need to Know

Scientific research strongly supports omega-3's benefits for testosterone levels. Men who eat more fish have substantially higher serum testosterone levels. Studies show remarkable differences between groups that eat low versus high amounts of fish . Research shows that lean fish helps boost testosterone levels in older males. The adjusted mean values rise from 5.63 ng/mL to 6.00 ng/mL when comparing the lowest to highest amounts eaten .

The link between fish oil and testosterone production matters especially when you have men over 60. Clinical trials reveal that DHA-enriched fish oil supplements can boost testosterone concentration in the blood compared to placebo groups . Fish oil seems to help overall male hormonal health too. Men who take these supplements show 20% lower follicle-stimulating hormone levels and an 8% higher free testosterone to luteinizing hormone ratio . These fatty acids support hormone synthesis through several pathways.

Older men often worry about their declining testosterone levels. They need to think over omega-3 supplementation's potential benefits. The right mix of EPA and DHA, correct dosing, and high-quality supplements are vital parts to maximise these essential fatty acids' hormonal benefits. This piece looks at how omega-3s and testosterone work together and why men over 60 should add these nutrients to their daily health routine.

How testosterone changes after 60

Graph showing testosterone levels naturally declining with age, illustrated by silhouettes of an overweight and a muscular man.

Image Source: Dr. Tashko

Most men don't realise their testosterone levels start dropping earlier than expected. Men's hormones change slowly and subtly, unlike women who experience dramatic shifts during menopause. Testosterone production starts to drop by about 1% each year between ages 30-40 [1]. By the time a man reaches 70, his testosterone levels are typically 30% lower than their peak [2].

Why testosterone matters for older men

Testosterone does more than control sexual function. This vital hormone affects many body systems that become more critical as men age. It helps regulate mood, brain function, metabolism, immune system, bone strength, and heart health [3].

Low testosterone levels can increase health risks. Research shows that men with low testosterone face higher chances of getting diabetes, dementia, heart disease, and might even die earlier [3]. These risks show why balanced hormone levels are vital after 60.

Testosterone helps preserve muscle mass that naturally decreases with age. This connection between testosterone and strength explains why staying fit gets harder as men grow older. The sort of thing I love is how certain foods can help - like the Mediterranean diet that supports testosterone levels by improving overall hormone health.

Common symptoms of low testosterone

About 10-15% of men over 60 have clinically low testosterone [4], and this number rises to 16-18% in men over 65 [1]. Many cases go undiagnosed because these symptoms look like normal ageing.

The most common signs of testosterone deficiency include:

  • Sexual changes: Lower sex drive, erectile problems, and fewer morning erections [5]

  • Physical alterations: Muscle loss, more belly fat, less body and facial hair, and unusual tiredness [5]

  • Psychological symptoms: Depression, irritability, lack of motivation, and problems with focus and memory [5]

  • Other signs: Hot flashes, sleep problems, weaker bones, and sometimes enlarged breast tissue (gynecomastia) [5]

Men who notice several of these symptoms might benefit from natural remedies for andropause along with medical advice.

How age affects hormone production

Age-related testosterone decline involves complex processes. The entire hormone control system - the hypothalamic-pituitary-gonadal axis - changes as we age [3].

The hypothalamus makes less gonadotropin-releasing hormone (GnRH) in older men, so the pituitary gland produces less luteinizing hormone (LH). Ageing Leydig cells in the testes don't respond as well to LH [3]. These cellular changes mean the body makes less testosterone even when hormone signals are present.

The testes themselves change with age. Older men have fewer Leydig cells [1] and more inflammation in testicular tissue [3]. These changes reduce testosterone production even further.

Sex hormone binding globulin (SHBG) increases with age. This protein attaches to testosterone in the blood, making it inactive. Even with normal total testosterone readings, less free (active) testosterone reaches the body's tissues [2].

Knowing how these age-related changes work helps us understand why natural approaches may support male hormone health, especially when it comes to omega-3 fatty acids' benefits for testosterone production in men over 60.

The role of omega-3 in testosterone production

Scientists have paid more attention to how dietary fats and hormone production work together over the last several years. Essential fatty acids, especially omega-3s, could help boost testosterone production in older men.

How fatty acids support hormone synthesis

The type and quality of dietary fats directly affect male hormone production. Polyunsaturated fatty acids change the makeup of cell membranes, including those in the Leydig cells of the testicles that produce testosterone [6]. These specialised cells need flexible membranes to respond well to hormonal signals.

Omega-3 fatty acids become part of Leydig cells' plasma membranes. This makes them respond better to luteinizing hormone and helps produce more testosterone [7]. The process works because omega-3s make cell membranes more flexible, which helps cells work better [7].

Scientists analysed a randomised controlled trial and found that omega-3 supplements increased total testosterone levels in overweight and obese men [6]. Higher testosterone levels matched the changes in omega-3 levels within red blood cell membranes, which tell us about overall cell membrane composition [7].

DHA and EPA: their specific functions

DHA and EPA, the two most active omega-3 fatty acids, seem to affect hormones differently.

DHA appears to help testosterone production the most. Men who took DHA-rich fish oil (860mg DHA and 120mg EPA daily) for 12 weeks showed much higher testosterone levels [8]. The control group taking corn oil didn't see these benefits [8].

The study showed that testosterone levels went up as EPA and DHA levels increased in red blood cell membranes [8]. These benefits might come from omega-3's ability to reduce inflammation, since research shows several negative links between testosterone and inflammatory cytokines [9].

Omega-3 and luteinizing hormone response

The hypothalamic-pituitary-gonadal axis controls testosterone production. Luteinizing hormone (LH) plays a vital role by telling the testes to make testosterone. Omega-3 fatty acids affect this system in various ways.

A study of 1,679 young Danish men showed that fish oil users had 16% less luteinizing hormone than non-users [10]. They also had an 8% higher free testosterone to LH ratio [10]. This suggests their testicles responded better to hormonal signals.

Not all studies show similar results. Some research shows omega-3 supplements increased luteinizing hormone levels [4], while others found they decreased [11]. These differences might come from different study groups, doses, or omega-3 types.

Men over 60 who experience natural symptoms of andropause might get extra benefits from omega-3s' anti-inflammatory properties. Age increases chronic inflammation and reduces testosterone production, but omega-3s are known to fight inflammation effectively [9].

Lean vs fatty fish: which is better for testosterone?

Fish choices can affect your hormonal health by a lot. Scientists have found surprising differences between lean and fatty fish that might change testosterone levels as men age.

Lean fish and testosterone: what the data shows

You might be surprised to learn that lean fish helps support testosterone more than fatty fish. A large study of older Japanese men found that eating more lean fish helped improve testosterone levels. Men who ate the most lean fish had adjusted mean testosterone levels of 6.00 ng/mL. Those who ate the least only reached 5.63 ng/mL [12].

The study showed this positive link specifically with lean fish, not the fatty varieties. The connection stayed strong even after scientists ruled out other factors that could affect testosterone production [13].

Fatty fish and environmental contaminants

Salmon and mackerel are famous for their omega-3s, but they might create unexpected hormone problems. Scientists think environmental pollutants in fatty fish could work against the natural testosterone boost from omega-3 fatty acids [12].

The main troublemakers are persistent organic pollutants such as dioxins and polychlorinated biphenyls (PCBs). These build up more in fatty fish than in lean ones [12]. Animal studies have shown these specific contaminants can lower testosterone levels directly [12].

Japanese adults who regularly eat fatty coastal fish, especially mackerel and sardines, tend to have higher levels of these hormone-disrupting compounds in their blood [12]. Research in the United States has also found that people with more PCBs in their blood make less testosterone [12].

Why lean fish may be safer for older men

Men over 60 already face natural testosterone decline. Lean fish could be a safer way to try natural remedies for andropause. It offers hormone benefits beyond just avoiding contaminants.

Studies show that men who eat more lean fish have lower triglycerides and more HDL (good) cholesterol [14]. These improvements in metabolism might help balance hormones since good heart health creates the foundation for making testosterone properly.

Heavy metals pose another risk for ageing men. Mercury, cadmium, and other toxic elements can stop important cells from making testosterone [1]. Lean fish typically carries fewer of these contaminants than fatty fish.

If you're following a Mediterranean diet for testosterone support, you might want to eat more lean fish and less fatty fish. This could give you the best hormone benefits while avoiding environmental pollutants.

Fish oil supplements: quality, purity, and effectiveness

Yellow translucent fish oil capsules scattered on a light blue background representing top supplements in 2025.

Image Source: Innerbody Research

Fish oil supplements show dramatic quality differences in the market. Men seeking hormonal benefits must choose their supplements carefully. The government's minimal regulations for supplement purity make third-party verification especially important.

How to choose a clean omega-3 supplement

The selection of an omega-3 supplement requires you to get into several factors beyond price:

  • Active ingredient content: Check EPA and DHA amounts per serving, not just total fish oil. Lower quality products contain just 30% omega-3s, while premium options offer up to 90% [15].

  • Freshness indicators: Quality supplements contain antioxidants like vitamin E with minimal fishy odour. This matters because oxidised fish oil loses its effectiveness and could become harmful.

  • Form of omega-3: Your body absorbs free fatty acids (FFA), triglycerides (TG), reformed triglycerides (rTG), or phospholipids (PLs) better than ethyl esters (EE) [15].

Understanding IFOS and purity certifications

IFOS (International Fish Oil Standards) certification stands as the gold standard to measure omega-3 quality. This 19-year old programme tests supplements for:

  • Potency (accurate EPA/DHA content)

  • Purity (absence of environmental contaminants)

  • Freshness (minimal oxidation) [16]

Independent laboratories test IFOS-certified products and display results publicly online. You can verify specific batch numbers before purchase [17]. The 5-star rating system clearly shows which supplements meet the highest quality standards.

Fish oil testosterone benefits vs risks

Studies show that DHA-enriched fish oil supplements (860mg DHA + 120mg EPA daily) substantially increased testosterone levels in men over 12 weeks [18]. These benefits depend on clean, high-quality products.

Environmental toxins like PCBs, dioxins, and heavy metals naturally build up in fish and pose the main risks. These contaminants might work against hormonal benefits, especially when you have men over 60 looking for natural remedies for andropause.

How much omega-3 do men over 60 need?

Illustration showing three types of omega-3 fatty acids: EPA from salmon, DHA from fish, and ALA from seeds and plants.

Image Source: VitaRx

Finding the right omega-3 intake is a vital step for men over 60 who want to support their hormonal health. Research keeps evolving, and several key guidelines help ageing men make smart choices about supplements.

Recommended daily intake of DHA and EPA

Men over 60 need to understand various expert recommendations to find the right balance of omega-3 fatty acids. The British Dietetic Association recommends about 450 mg of combined EPA and DHA daily [19]. This equals roughly two servings of oily fish each week. Adult guidelines generally suggest between 1,000 to 2,000 mg of combined EPA and DHA per day [20].

The Scientific Advisory Committee on Nutrition (SCAN) also backs a daily intake of 450 mg EPA and DHA combined [5]. These recommendations meet at this level, which seems right for most older men. Men focused on testosterone support might need to think over different approaches.

Medical guidance suggests that men over 60 should stick to the lower end of recommended amounts - about 250 milligrammes of EPA and DHA daily [21]. This changes based on health conditions. Doctors might recommend up to 15 grammes for men with hypertension or 10 grammes for those with rheumatoid arthritis [21].

EPA vs DHA ratios for hormonal health

EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) ratios need careful attention. Each component helps male hormonal health differently. Clinical studies show DHA has stronger links to testosterone production, so men over 60 might benefit more from formulas with higher DHA levels.

No perfect EPA:DHA ratio exists for general health benefits. Research into natural remedies for andropause suggests that DHA-rich formulas could work better for testosterone support.

The sort of thing I love is how DHA converts back to EPA in the body [5]. This makes DHA-focused supplements more versatile for overall hormonal health. This matters especially for men who follow plant-based versions of the Mediterranean diet for testosterone.

When to take omega-3 for best absorption

The right timing of omega-3 supplements can improve their effectiveness substantially. Research shows one main rule: take omega-3 supplements with fatty meals [22]. This helps absorption because your body releases digestive enzymes that break down fats.

Taking fish oil right before meals helps reduce acid reflux and indigestion [23]. These are common issues for men over 60. If you get reflux or fishy aftertaste, try splitting your daily dose - half before breakfast and half before dinner [22].

A regular routine works better than perfect timing. The benefits of omega-3 fatty acids show up through steady use rather than quick effects [23]. Your best approach to supporting male hormonal health naturally is finding a schedule that fits your daily routine.

Conclusion

Omega-3 fatty acids and testosterone production share a promising connection that benefits men beyond age 60. Studies show these essential fatty acids boost hormone production in multiple ways. They improve Leydig cell membrane flexibility and make cells more responsive to luteinizing hormone. DHA proves especially beneficial for testosterone synthesis, and research reveals notable hormonal improvements from DHA-enriched supplements.

You might be surprised by the differences between fish types. Lean fish supports testosterone levels better than fatty fish varieties, which goes against common belief. This happens because fatty fish often contains environmental contaminants that work against natural hormonal benefits. Men looking into natural remedies for andropause should add more lean fish to their diet.

Quality matters a lot when choosing supplements. Third-party certifications like IFOS help ensure purity and potency. Supplements with free fatty acids or triglycerides work better than ethyl esters because your body absorbs them more easily. The supplement form you choose matters just as much as how much you take.

Most men over 60 need about 450mg of combined EPA and DHA daily, though this varies based on health conditions. Your body absorbs these supplements best with fatty meals. Regular intake matters more than specific timing for long-term hormonal benefits.

Of course, omega-3 supplements alone can't completely stop age-related testosterone decline. But these essential fatty acids become powerful tools for hormonal support when combined with other natural remedies for male andropause and low testosterone. Following a Mediterranean diet for testosterone support could bring extra benefits through better nutrition.

Research shows omega-3 fatty acids should be part of your comprehensive plan for hormonal health after 60. These fatty acids support testosterone production while protecting your heart and fighting inflammation. This makes them valuable for older men who want to stay healthy and energetic.

Key Takeaways

Understanding the connection between omega-3 fatty acids and testosterone can help men over 60 make informed decisions about supporting their hormonal health naturally.

• Men consuming higher amounts of fish show significantly elevated testosterone levels, with lean fish proving more beneficial than fatty varieties for hormone production.

• DHA-enriched supplements (860mg DHA + 120mg EPA daily) can increase testosterone levels in men, whilst improving cellular responsiveness to hormonal signals.

• Choose lean fish over fatty fish to avoid environmental contaminants like PCBs and dioxins that may counteract testosterone-supporting benefits.

• Quality matters enormously—select IFOS-certified supplements containing triglycerides or free fatty acids rather than ethyl esters for optimal absorption.

• Aim for 450mg combined EPA and DHA daily, taken with fat-containing meals for maximum effectiveness and minimal digestive discomfort.

Whilst omega-3s alone cannot reverse age-related testosterone decline, they represent a valuable component of a comprehensive approach to maintaining hormonal health after 60. Combined with other natural strategies, these essential fatty acids offer both direct testosterone support and broader health benefits including cardiovascular protection and anti-inflammatory effects.

FAQs

Q1. What is the recommended omega-3 intake for men over 60? Most guidelines suggest around 450 mg of combined EPA and DHA daily for men over 60. This is roughly equivalent to two servings of oily fish per week. However, individual needs may vary based on specific health conditions, so it's best to consult with a healthcare provider for personalised recommendations.

Q2. Can omega-3 fatty acids help increase testosterone levels in older men? Yes, research indicates that omega-3 fatty acids, particularly DHA, can support testosterone production in men. Studies have shown that DHA-enriched fish oil supplements can increase testosterone concentration in the blood compared to placebo groups, potentially benefiting men experiencing age-related hormonal changes.

Q3. Is lean fish or fatty fish better for testosterone support in men over 60? Surprisingly, lean fish consumption has been more strongly associated with improved testosterone levels in older men. This is likely due to lower levels of environmental contaminants like PCBs and dioxins, which can accumulate in fatty fish and potentially counteract hormonal benefits.

Q4. How can men ensure they're choosing a high-quality omega-3 supplement? Look for supplements with third-party certifications like IFOS (International Fish Oil Standards), which test for purity, potency, and freshness. Choose products containing free fatty acids or triglycerides rather than ethyl esters for better absorption. Pay attention to the specific amounts of EPA and DHA per serving, not just total fish oil content.

Q5. When is the best time to take omega-3 supplements for optimal absorption? For best absorption, take omega-3 supplements with meals that contain fat. This triggers the release of digestive enzymes that help break down and absorb the fatty acids. Some people find taking the supplement immediately before meals helps reduce the risk of acid reflux. Consistency in daily intake is more important than specific timing for long-term benefits.

References

[1] - https://onlinelibrary.wiley.com/doi/10.1155/2024/4680357
[2] - https://www.health.harvard.edu/newsletter_article/testosterone_aging_and_the_mind
[3] - https://pmc.ncbi.nlm.nih.gov/articles/PMC11562514/
[4] - https://pmc.ncbi.nlm.nih.gov/articles/PMC5312216/
[5] - https://www.nmi.health/epa-dha-a-review-of-clinical-use-and-efficacy/
[6] - https://pubmed.ncbi.nlm.nih.gov/33221700/
[7] - https://www.foundmyfitness.com/stories/kuswa2/epa_and_dha_supplementation_increases_serum_testosterone_levels_in_males_with_overweight_and_obesity
[8] - https://www.omegor.com/en/blogs/fertility/omega-3-and-testosterone-dha-increases-testosterone-level-in-men?srsltid=AfmBOoqzUK82BXxeQmHokw1n4A0iBz-Peaj3TE4qOwN81eCCmYyyQfRu
[9] - https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.71062
[10] - https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2758861
[11] - https://pmc.ncbi.nlm.nih.gov/articles/PMC8260291/
[12] - https://pmc.ncbi.nlm.nih.gov/articles/PMC10997911/
[13] - https://pubmed.ncbi.nlm.nih.gov/38584675/
[14] - https://pmc.ncbi.nlm.nih.gov/articles/PMC5372910/
[15] - https://www.healthline.com/nutrition/omega-3-supplement-guide
[16] - https://certifications.nutrasource.ca/about/how-certifications-work/ifos
[17] - https://www.nutrasource.ca/certifications-by-nutrasource/international-fish-oil-standards-ifos/
[18] - https://www.sciencedirect.com/science/article/abs/pii/S0952327820301629
[19] - https://www.thefemalehealthdoctor.com/omega-3-and-womens-health-why-it-matters-and-how-to-choose-the-right-supplement/
[20] - https://www.drlouisenewson.co.uk/knowledge/omega-3-menopause-and-hormone-health
[21] - https://www.webmd.com/healthy-ageing/what-to-know-about-fish-oil-dosage-for-older-adults?utm_source=direct&utm_medium=direct&utm_campaign=direct&utm_content=direct&utm_term=direct
[22] - https://www.eatingwell.com/best-time-to-take-omega-3-supplement-11829922
[23] - https://www.healthline.com/nutrition/best-time-to-take-fish-oil

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